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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
TP53BP1
All Species:
14.24
Human Site:
S1497
Identified Species:
52.22
UniProt:
Q12888
Number Species:
6
Phosphosite Substitution
Charge Score:
-0.17
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q12888
NP_001135451.1
1972
213574
S1497
R
V
V
A
K
W
S
S
N
G
Y
F
Y
S
G
Chimpanzee
Pan troglodytes
XP_001158270
1972
213535
S1497
R
V
V
A
K
W
S
S
N
G
Y
F
Y
S
G
Rhesus Macaque
Macaca mulatta
XP_001107220
1972
213653
S1497
R
V
V
A
K
W
S
S
N
G
Y
F
Y
S
G
Dog
Lupus familis
XP_849774
1976
214088
S1501
R
V
V
A
K
W
S
S
N
G
Y
F
Y
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Rat
Rattus norvegicus
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001082071
2104
231430
T1621
P
P
A
R
G
A
G
T
R
D
N
T
A
N
T
Zebra Danio
Brachydanio rerio
NP_001073639
1709
184731
K1258
V
G
L
R
V
L
A
K
W
S
S
N
S
Y
F
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_798355
2169
238737
M1615
V
R
V
F
T
R
W
M
D
G
F
Y
Y
P
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.2
97.2
89.2
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
36.9
34.4
N.A.
N.A.
N.A.
N.A.
20.5
Protein Similarity:
100
99.5
98.2
93.6
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
54.5
51.3
N.A.
N.A.
N.A.
N.A.
37.6
P-Site Identity:
100
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
0
0
N.A.
N.A.
N.A.
N.A.
26.6
P-Site Similarity:
100
100
100
100
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
13.3
13.3
N.A.
N.A.
N.A.
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
15
58
0
15
15
0
0
0
0
0
15
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
0
15
15
0
0
0
0
0
% D
% Glu:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% E
% Phe:
0
0
0
15
0
0
0
0
0
0
15
58
0
0
15
% F
% Gly:
0
15
0
0
15
0
15
0
0
72
0
0
0
0
72
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
0
0
58
0
0
15
0
0
0
0
0
0
0
% K
% Leu:
0
0
15
0
0
15
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
15
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
58
0
15
15
0
15
0
% N
% Pro:
15
15
0
0
0
0
0
0
0
0
0
0
0
15
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
58
15
0
29
0
15
0
0
15
0
0
0
0
0
0
% R
% Ser:
0
0
0
0
0
0
58
58
0
15
15
0
15
58
0
% S
% Thr:
0
0
0
0
15
0
0
15
0
0
0
15
0
0
15
% T
% Val:
29
58
72
0
15
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
58
15
0
15
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
58
15
72
15
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _